Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in two patients under antiretroviral therapy

Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in two patients under antiretroviral therapy

One of the approaches to remedy human immunodeficiency virus (HIV) is the use of therapeutic vaccination. We have launched the Provir/Latitude 45 examine to establish conserved CTL epitopes in archived HIV-1 DNA based on the HLA class I alleles in aviremic patients under antiretroviral therapy (ART). A HIV-1 polypeptidic therapeutic vaccine primarily based on viral sequence knowledge obtained from circulating blood was proposed; right here, our intention was to check the proviral DNA in blood and gut-associated lymphoid tissue (GALT).

Peripheral blood mononuclear cells and intestine biopsies had been obtained from two HIV-1 contaminated patients under profitable antiretroviral therapy. Total DNA was extracted together with the proviral DNA. The HIV-1 reverse transcriptase was sequenced in each compartments utilizing subsequent technology sequencing adopted by single genome sequencing; phylogenetic bushes had been established and in contrast. The proviral sequences of each compartments intra-patient exhibited a really low genetic divergence whereas it was potential to distinguish the sequences inter-patients; single genome sequencing analysis of two {couples} of samples confirmed that there was no compartmentalization of the sequences intra-patient.

We conclude that, contemplating these two instances, the proviral DNA sequences in blood and GALT are comparable and that the epitope analysis of HIV-1 provirus in blood must be thought-about as related to that noticed in the GALT, a hard-to-reach main compartment, and can subsequently be used for therapeutic vaccine approaches. Phylogenetically corrected strategies recognized a complete of 161 HLA-associated polymorphisms; whereby Nef and Vpu had the very best (26.6%) and lowest (1.2%) proportion of amino acid websites related to HLA-class I alleles, respectively.

HIV-1 escapes by buying mutations that differentially affect the course of an infection. Unlike HIV-1 structural and enzymatic proteins, it stays elusive what extent the host immune-mediated choice stress influences the variability of the accent (Vif, Vpu, Vpr, and Nef) and regulatory (Tat and Rev) proteins. To tackle this, we analysed the viral sequences encoding accent and regulatory proteins from 446 HLA-typed, chronically HIV-1 subtype B-infected, and remedy naïve people in Japan. We noticed that Vpu and Vpr had been essentially the most and least polymorphic proteins with the common Shannon entropy scores of 0.63 and 0.38, respectively. These outcomes add additional perception on the position of HLA-mediated choice stress on HIV-1 sequence polymorphisms of HIV-1 accent and regulatory proteins.

Per-protocol analysis of the ZINC trial for HIV illness amongst alcohol customers
The Zinc for INflammation and Chronic illness in HIV (ZINC) trial randomized one who reside with HIV (PLWH) who have interaction in heavy ingesting to both each day zinc supplementation or placebo. The main end result was change in the Veterans Aging Cohort Study (VACS) index, a predictor of mortality, between baseline and 18 months. Because adherence and follow-up had been suboptimal, the intention-to-treat analysis, which was not statistically important, could have underestimated the impact of the zinc supplementation. We estimated the per-protocol impact of zinc versus placebo in the ZINC trial (i.e., the impact that will have been noticed if all contributors had had excessive adherence and none was misplaced to follow-up).
Adherence was measured because the self-reported share of drugs taken in the earlier 6 weeks and assessed in any respect post-baseline visits. We used inverse chance weighting to estimate and examine the change in the VACS index at 18 months in the zinc and placebo teams, had all of the trial contributors had excessive adherence (i.e., cumulative adherence ≥80% at 18 months). To look at tendencies by stage of adherence, we rerun the analyses utilizing thresholds for prime adherence of 70% and 90% of common self-reported tablet protection. Overall, excessive adherence to zinc was related to a decrease VACS rating, however confidence intervals had been huge and crossed 0. Further research with a bigger pattern dimension are wanted to quantify the advantages of zinc supplementation in this inhabitants.
The estimated (95% confidence interval) change in the VACS index was – 2.16 (- 8.07, 3.59) and 5.84 (0.73, 11.80) under excessive adherence and no loss to follow-up in the zinc and placebo teams, respectively. The per-protocol impact estimate of the imply distinction in the change between the zinc and placebo teams was – 8.01 (- 16.42, 0.01), considerably bigger than the intention-to-treat impact distinction in change (- 4.68 (- 9.62, 0.25)), however it was nonetheless not statistically important. The imply distinction in the change between people in the zinc and placebo teams was – 4.07 (- 11.5, 2.75) and -12.34 (- 20.14, -4.14) for prime adherence outlined as 70% and 90% of tablet protection, respectively.
Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in two patients under antiretroviral therapy
Exclusion of patients residing with HIV from most cancers immune checkpoint inhibitor trials
Emerging retrospective and potential research point out that immune checkpoint inhibitors (ICIs) may be protected and efficient most cancers remedies amongst individuals residing with human immunodeficiency virus (PLWH), nevertheless this high-cancer-risk inhabitants has typically been excluded from groundbreaking most cancers ICI trials. Our examine aimed to characterize the present fee of exclusion and conditional inclusion of PLWH in most cancers ICI trials by tumor sort, trial part, and yr. MedicalTrials.gov most cancers ICI trials with deliberate begins between 1/1/2019 and 10/20/2020 had been recognized.
Based on trial eligibility standards, trials had been categorized as “excluded” if PLWH couldn’t enroll, “conditionally included” if solely PLWH with enough immune operate had been allowed, or “included/not specified” if HIV was not talked about in the eligibility standards. Trials from 2014 had been individually collected for comparability over time. The quantity of trials excluding PLWH had been in comparison with the included/not specified group utilizing Fisher’s precise take a look at. Of 809 trials analyzed from 2019 to 2020, 74.4% excluded, 6.9% conditionally included, and 18.7% included/didn’t specify PLWH. Early part trials excluded PLWH extra often than late part trials.

EZScreen? Beta-Lactamase Activity Colorimetric Assay Kit (384-well)

K954-400 each
EUR 874.8

Amplite® Colorimetric Beta-Lactamase Activity Assay Kit

12551 200 Tests
EUR 455
Description: β-Lactamases are a large family of enzymes capable of hydrolyzing β-lactams.

Amplite® Colorimetric Beta-Lactamase Activity Assay Kit

12551-200Tests 200 Tests
EUR 446
Description: β-Lactamases are a large family of enzymes capable of hydrolyzing β-lactams.

Lactate Dehydrogenase Activity Colorimetric Assay Kit

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EUR 660

HAT Activity Colorimetric Assay Kit

K2033-100 100 assays
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Description: Detects HAT activity, sensitive and non-radioactive.

HAT Activity Colorimetric Assay Kit

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EUR 646.8

HDAC Activity Colorimetric Assay Kit

K2032-100 100 assays
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HDAC Activity Colorimetric Assay Kit

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EUR 389
Description: Detects HDAC activity, high throughput screening (HTS).

HDAC Activity Colorimetric Assay Kit

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Lipase Activity Colorimetric Assay Kit

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EUR 470
Description: Detects lipase activity, sensitive, high throughput screening (HTS).

Lipase Activity Colorimetric Assay Kit

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Trypsin Activity Colorimetric Assay Kit

K2176-100 100 assays
EUR 409
Description: Sensitive, Colorimetric Assay

Trypsin Activity Colorimetric Assay Kit

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Amylase Activity Colorimetric Assay Kit

K2225-100 100 assays
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Description: Detects amylase activity, sensitive.

Amylase Activity Colorimetric Assay Kit

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EUR 489.6

Aldolase Activity Colorimetric Assay Kit

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Arginase Activity Colorimetric Assay Kit

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Fumarase Activity Colorimetric Assay Kit

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EZScreen? Lactate Dehydrogenase Activity Colorimetric Assay Kit (384-well)

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Aconitase Activity Colorimetric Assay Kit

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Aconitase Activity Colorimetric Assay Kit

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Description: Detects aconitase activity, highly sensitive, high throughput screening (HTS).

Invertase Activity Colorimetric Assay Kit

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Collagenase Activity Colorimetric Assay Kit

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?-Glucosidase Activity Colorimetric Assay Kit

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Lipase Activity Colorimetric Assay Kit II

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Caspase 3 Activity Colorimetric Assay Kit

E-CK-A311-100Assays 100 Assays
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Caspase 3 Activity Colorimetric Assay Kit

E-CK-A311-20Assays 20 Assays
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Caspase 3 Activity Colorimetric Assay Kit

E-CK-A311-50Assays 50 Assays
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Caspase 8 Activity Colorimetric Assay Kit

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Caspase 8 Activity Colorimetric Assay Kit

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Caspase 8 Activity Colorimetric Assay Kit

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Caspase 9 Activity Colorimetric Assay Kit

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Caspase 9 Activity Colorimetric Assay Kit

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EUR 68

Caspase 9 Activity Colorimetric Assay Kit

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GST Colorimetric Activity Assay Kit

55R-1353 100 assays
EUR 540
Description: Assay Kit for detection of GST activity in the research laboratory

GST Colorimetric Activity Assay Kit

GWB-AXR176 100 assays Ask for price

GST Colorimetric Activity Assay Kit

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GST Colorimetric Activity Assay Kit

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Ceruloplasmin Activity Colorimetric Assay Kit

K669-100 each
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HDAC Colorimetric Activity Assay Kit

GWB-AXR200 100 assays Ask for price

Cathepsin G Activity Colorimetric Assay Kit

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Sphingomyelinase Activity Colorimetric Assay Kit

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Urease Activity Assay Kit (Colorimetric)

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ATPase Activity Assay Kit (Colorimetric)

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GST Colorimetric Activity Assay

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EUR 527

Plasmin Activity Assay Kit (Colorimetric)

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Acid Phosphatase Activity Colorimetric Assay Kit

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Citrate Synthase Activity Colorimetric Assay Kit

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Description: Detects citrate synthase activity.

Citrate Synthase Activity Colorimetric Assay Kit

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Acid Phosphatase Activity Colorimetric Assay Kit

K411-500 each
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Sulfatase Activity Assay Kit (Colorimetric)

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Acetylcholinesterase Activity Colorimetric Assay Kit

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Cytochrome Oxidase Activity Colorimetric Assay Kit

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EUR 485
Description: Detects cytochrome oxidase activity, high throughput screening (HTS).

Cytochrome Oxidase Activity Colorimetric Assay Kit

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Tyrosinase Activity Assay Kit (Colorimetric)

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Alkaline Phosphatase Activity Colorimetric Assay Kit

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Alkaline Phosphatase Activity Colorimetric Assay Kit

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EUR 557
Description: Detects alkaline phosphatase activity, highly sensitive, high throughput screening (HTS).

Malate Dehydrogenase Activity Colorimetric Assay Kit

K2206-100 100 assays
EUR 600
Description: Detects malate dehydrogenase activity, highly sensitive.

Malate Dehydrogenase Activity Colorimetric Assay Kit

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Alkaline Phosphatase Activity Colorimetric Assay Kit

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Creatine Kinase (CK) Activity Colorimetric Assay Kit

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Factor XIa Activity Assay Kit (Colorimetric)

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Oxalate Decarboxylase Activity Colorimetric Assay Kit

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Glutathione Reductase Activity Colorimetric Assay Kit

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EUR 542
Description: Highly Sensitive Assay, HTS

Thioredoxin Reductase Activity Colorimetric Assay Kit

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EUR 542
Description: Sensitive, Colorimetric Assay

Thioredoxin Reductase Activity Colorimetric Assay Kit

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Glucose Dehydrogenase Activity Colorimetric Assay Kit

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Alcohol Dehydrogenase Activity Colorimetric Assay Kit

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Glutathione Reductase Activity Colorimetric Assay Kit

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Factor XIIa Activity Assay Kit (Colorimetric)

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Aldehyde Dehydrogenase Activity Colorimetric Assay Kit

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Glutathione Peroxidase Activity Colorimetric Assay Kit

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EUR 586
Description: Sensitive, Colorimetric Assay

Glutathione Peroxidase Activity Colorimetric Assay Kit

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Aldehyde Dehydrogenase Activity Colorimetric Assay Kit

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Phospholipase D (PLD) Activity Colorimetric Assay Kit

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Cholinesterase Activity Assay Kit (Colorimetric)

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Factor XIIIa Activity Assay Kit (Colorimetric)

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Phosphofructokinase (PFK) Activity Colorimetric Assay Kit

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Succinate Dehydrogenase Activity Colorimetric Assay Kit

K2210-100 100 assays
EUR 610
Description: Detects succinate dehydrogenase activity, sensitive, high throughput screening (HTS).

Glutamate Dehydrogenase Activity Colorimetric Assay Kit

K2229-100 100 assays
EUR 436
Description: Detects glutamate dehydrogenase (GDH) activity, sensitive.

Succinate Dehydrogenase Activity Colorimetric Assay Kit

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Glutamate Dehydrogenase Activity Colorimetric Assay Kit

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Phosphoglucose Isomerase Activity Colorimetric Assay Kit

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Isocitrate Dehydrogenase Activity Colorimetric Assay Kit

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Glyoxalase I Activity Assay Kit (Colorimetric)

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Transglutaminase Activity Assay Kit (Colorimetric)

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Enolase Activity Colorimetric/Fluorometric Assay Kit

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Methyltransferase Activity Assay Kit (Colorimetric)

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Mitochondrial Complex I Activity Colorimetric Assay Kit

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Superoxide Dismutase (SOD) Activity Colorimetric Assay Kit

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Caspase1 Activity Assay Kit(Colorimetric Method)

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Caspase1 Activity Assay Kit(Colorimetric Method)

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EUR 68

Caspase1 Activity Assay Kit(Colorimetric Method)

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Caspase2 Activity Assay Kit(Colorimetric Method)

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Caspase2 Activity Assay Kit(Colorimetric Method)

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Caspase2 Activity Assay Kit(Colorimetric Method)

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Caspase4 Activity Assay Kit(Colorimetric Method)

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Caspase4 Activity Assay Kit(Colorimetric Method)

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Caspase4 Activity Assay Kit(Colorimetric Method)

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EUR 136

Caspase6 Activity Assay Kit(Colorimetric Method)

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Caspase6 Activity Assay Kit(Colorimetric Method)

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EUR 68

Caspase6 Activity Assay Kit(Colorimetric Method)

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Caspase8 Activity Assay Kit(Colorimetric Method)

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Caspase8 Activity Assay Kit(Colorimetric Method)

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EUR 68

Caspase8 Activity Assay Kit(Colorimetric Method)

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EUR 136

Caspase9 Activity Assay Kit(Colorimetric Method)

E-CK-A389-100Assays 100 Assays
EUR 228

Caspase9 Activity Assay Kit(Colorimetric Method)

E-CK-A389-20Assays 20 Assays
EUR 68

Caspase9 Activity Assay Kit(Colorimetric Method)

E-CK-A389-50Assays 50 Assays
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5?-Nucleotidase Activity Assay Kit (Colorimetric)

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Catalase Activity Colorimetric/Fluorometric Assay Kit

K2177-100 100 assays
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Description: Highly Sensitive Assay, HTS

Catalase Activity Colorimetric/Fluorometric Assay Kit

K773-100 each
EUR 502.8

Succinyl-CoA Synthetase Activity Colorimetric Assay Kit

K597-100 each
EUR 940.8

HRV 3C Protease Activity Assay Kit (Colorimetric)

K214-100 each
EUR 679.2

Pyruvate Dehydrogenase (PDH) Activity Colorimetric Assay Kit

K2218-100 100 assays
EUR 769.2

Pyruvate Dehydrogenase (PDH) Activity Colorimetric Assay Kit

K2218-96 96 tests
EUR 494
Description: Detects alpha-ketoglutarate dehydrogenase activity.

Pyruvate Dehydrogenase (PDH) Activity Colorimetric Assay Kit

K679-100 each
EUR 732

Plasma Kallikrein Activity Assay Kit (Colorimetric)

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EUR 744

Glucose Isomerase Activity Assay Kit (Colorimetric)

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EUR 588

Peroxidase Activity Colorimetric/Fluorometric Assay Kit

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EUR 464.4

Gluconokinase (GntK) Activity Assay Kit (Colorimetric)

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EUR 874.8

Catalase Colorimetric Activity Kit (2 Plate)

K033-H1 2 x 96 well plate
EUR 425
Description: Catalase Colorimetric Activity assay Kit

Caspase 1 Activity Assay Kit(Colorimetric Method)

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Description: Apoptosis/Caspase

Caspase 2 Activity Assay Kit(Colorimetric Method)

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Description: Apoptosis/Caspase

Caspase 4 Activity Assay Kit(Colorimetric Method)

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Description: Apoptosis/Caspase

Caspase 6 Activity Assay Kit(Colorimetric Method)

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Description: Apoptosis/Caspase

Caspase 8 Activity Assay Kit(Colorimetric Method)

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Description: Apoptosis/Caspase

Caspase 9 Activity Assay Kit(Colorimetric Method)

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Description: Apoptosis/Caspase

Myeloperoxidase (MPO) Colorimetric Activity Assay Kit

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Adenosine Deaminase Activity Assay Kit (Colorimetric)

K321-100 each
EUR 502.8

PAF Acetylhydrolase Activity Assay Kit (Colorimetric)

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Myeloperoxidase (MPO) Colorimetric Activity Assay Kit

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EUR 600
Description: Sensitive Assay, HTS

Myeloperoxidase (MPO) Colorimetric Activity Assay Kit

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The 2019-2020 trial cohort confirmed no important change in exclusion of PLWH in comparison with 2014. Despite growing proof for protected and efficient ICI use for PLWH, most most cancers ICI trials exclude PLWH and few research allow PLWH to take part, even when HIV is well-controlled.

Motivations to use hormonal contraceptive methods and condoms among HIV-positive and negative women randomized to a progestin contraceptive in Malawi: a qualitative study

Motivations to use hormonal contraceptive methods and condoms among HIV-positive and negative women randomized to a progestin contraceptive in Malawi: a qualitative study
Although many international locations have been selling hormonal contraceptives to stop unintended being pregnant and condom use to stop HIV transmission, little is understood about how women focused by these messages have interpreted and internalized them. We describe HIV-positive and negative women’s understanding of the advantages of contraception and condoms and their motivations to use them. This is a qualitative sub-study from a scientific trial evaluating the results of progestin contraception on HIV-positive and negative women aged 18-45 years randomly assigned to depot medroxyprogesterone acetate (DMPA) injection or levonorgestrel (LNG) implant.
We purposively recruited 41 women to take part in in-depth interviews (IDIs) and focus group discussions (FGDs) after randomization into the principle study. We carried out a complete of 30 IDIs and 6 FGDs comprised of 4-7 women (N = 32). All women had been counselled about potential dangers for HIV acquisition/transmission with progestin-only contraception, drug-drug interactions between the implant and efavirenz-based ART, and the necessity to use condoms with their assigned contraceptive to assist stop being pregnant and HIV acquisition and transmission.
All women understood that HIV is transmitted via unprotected intercourse and that HIV transmission will be prevented via condom use however not DMPA injection or LNG implant use. Nearly all HIV-positive women knew or suspected that their companions had been additionally HIV-positive and had been most in utilizing condoms to stop an infection with a drug-resistant HIV pressure to preserve their HIV viral load low. Almost all reported that their companions agreed to condom use, however few used them constantly. Most women believed that condoms had been efficient at stopping each HIV and being pregnant if used constantly.
Nearly all women thought of contraception and condom use as essential in stopping unintended being pregnant and HIV as a result of associate disclosure of HIV standing is low. Our outcomes confirmed that each HIV-positive and negative women understood modes of HIV transmission and prevention and had been conscious that hormonal contraceptives are solely efficient for stopping being pregnant and not HIV. Although each HIV-negative and constructive women had been motivated to use condoms to stop each HIV acquisition and an infection with different HIV strains respectively, all of them confronted challenges from their companions in utilizing condoms constantly.

Multi-level issues for optimum implementation of long-acting injectable antiretroviral remedy to deal with individuals residing with HIV: views of well being care suppliers collaborating in part Three trials

Long-acting injectable antiretroviral remedy (LA ART) has been proven to be non-inferior to each day oral ART, with excessive affected person satisfaction and choice to oral customary of care in analysis to date, and has lately been accepted for use in the United States and Europe. This study examined the views of well being care suppliers collaborating in LA ART scientific trials on potential obstacles and options to LA ART roll-out into actual world settings. This evaluation attracts on two knowledge sources: (1) open-ended questions embedded in a structured on-line survey of 329 well being care suppliers collaborating in the ATLAS-2 M trial throughout 13 international locations; and (2) in-depth interviews with 14 suppliers collaborating in FLAIR/ ATLAS/ATLAS-2 M trials in the United States and Spain.
 Barriers and proposed options to LA ART implementation had been recognized on the particular person, clinic and well being system ranges. Provider perceptions of affected person stage obstacles included challenges with adhering to frequent injection appointments and injection tolerability. Proposed options included affected person training, having designated workers for clinic go to retention, and clinic flexibility with appointment scheduling. The most important supplier concern was figuring out applicable candidates for LA ART; proposed options centered on affected person supplier communication and choice making. Clinic stage obstacles included the necessity for added expert people to administer injections, shifts in workflow as demand will increase and the logistics of cold-chain storage.
Proposed options included workers hiring and coaching, strategic planning round workflow and logistics, and the potential of providing injections in different settings, together with the house. Health system stage obstacles included price and approvals from nationwide regulatory our bodies. Potential options included governments subsidizing therapy, guaranteeing price is aggressive with oral ART, and providing co-pay help. Results counsel the significance of multi-level assist techniques to optimize patient-provider communication and therapy decision-making; clinic staffing, workflow, logistics protocols and infrastructure; and cost-related elements inside a given well being system.
Motivations to use hormonal contraceptive methods and condoms among HIV-positive and negative women randomized to a progestin contraceptive in Malawi: a qualitative study

Using Incentives and Nudging to Improve Non-Targeted HIV Testing in Ecuador: A Randomized Trial

Under-detection of HIV/AIDS nonetheless burdens many low- and middle-income international locations (LMICs). Our randomized trial investigated the results of economic incentives and a behavioral nudge to induce HIV testing and studying HIV standing in Ecuador. In the management group, 12.2% of members agreed to testing, and 5.3% discovered outcomes. A monetary incentive paid at testing elevated the fraction of members examined by 50.1 share factors (95% CI 38.8 to 61.4) and the fraction who discovered their standing by 8.9 share factors (95% CI 5.3 to 12.5); the nudge had no impact.

Cell Meterâ„¢ Colorimetric Cell Cytotoxicity Assay Kit
22780-1000Tests 1000 Tests
EUR 222
Description: Monitoring cell cytotoxicity is one of the most essential tasks for studying cellular functions.
Sulforhodamine B Cell Cytotoxicity Assay Kit (Colorimetric)
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EUR 379.2
LDH Cytotoxicity Assay Kit
18250-35 500TESTS
EUR 217
LDH Cytotoxicity Assay Kit
18250-64 100TESTS
EUR 101.5
LDH Cytotoxicity Assay Kit
55R-1366 400 assays
EUR 413
Description: Assay Kit for detection of LDH Cytotoxicity in the research laboratory
LDH Cytotoxicity Assay Kit
55R-1368 500 assays
EUR 453
Description: Assay Kit for detection of LDH Cytotoxicity in the research laboratory
LDH Cytotoxicity Assay Kit
C2LD-100 100
EUR 129
LDH Cytotoxicity Assay Kit
K6330400 400 assays
EUR 367.2
Description: Premade ready to use kits will always come in handy. Get your experiment done right form the first try by using a validated kit with perfectly balanced reagents proportions and compatibility and by following a clear protocol.
LDH Cytotoxicity Assay Kit
KTA1030-480T 480 T
EUR 199
Description: Abbkine LDH Cytotoxicity Assay Kit provides a simple and easy colorimetric assay for the study of cytotoxicity.
LDH Cytotoxicity Assay Kit
KTA1030-96T 96 T
EUR 89
Description: Abbkine LDH Cytotoxicity Assay Kit provides a simple and easy colorimetric assay for the study of cytotoxicity.
LDH Cytotoxicity Assay Kit
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LDH Cytotoxicity Assay
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EUR 290
LDH-Cytotoxicity Colorimetric Assay Kit
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EUR 346
Description: Detects cytotoxicity, sensitive.
LDH-Cytotoxicity Colorimetric Assay Kit
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Caspase-3 Colorimetric Assay Kit - 400 assays
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Caspase-8 Colorimetric Assay Kit - 400 assays
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Caspase-5 Colorimetric Assay Kit - 400 assays
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Caspase-4 Colorimetric Assay Kit - 400 assays
GWB-AXR088 400 assays Ask for price
Caspase-10 Colorimetric Assay Kit - 400 assays
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LDH-Cytotoxicity Colorimetric Assay Kit II
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EUR 437
Description: Detects cytotoxicity, sensitive.
LDH-Cytotoxicity Colorimetric Assay Kit II
K313-500 each
EUR 502.8
Genorise® LDH Cytotoxicity Assay Kit
GR107034 1000 tests
EUR 289
CytoSelect™ LDH Cytotoxicity Assay Kit
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EUR 320
Cytotoxicity LDH Assay Kit(WST-8 one step)
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EUR 225
Caspase-3 Colorimetric Assay Kit - 100 assays
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Caspase-3 Colorimetric Assay Kit - 200 assays
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Caspase-1 Colorimetric Assay Kit - 100 assays
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Caspase-1 Colorimetric Assay Kit - 200 assays
GWB-AXR029 200 assays Ask for price
Caspase-8 Colorimetric Assay Kit - 100 assays
GWB-AXR036 100 assays Ask for price
Caspase-8 Colorimetric Assay Kit - 200 assays
GWB-AXR037 200 assays Ask for price
Caspase-6 Colorimetric Assay Kit - 100 assays
GWB-AXR044 100 assays Ask for price
Caspase-6 Colorimetric Assay Kit - 200 assays
GWB-AXR045 200 assays Ask for price
Caspase-2 Colorimetric Assay Kit - 100 assays
GWB-AXR052 100 assays Ask for price
Caspase-2 Colorimetric Assay Kit - 200 assays
GWB-AXR053 200 assays Ask for price
Caspase-9 Colorimetric Assay Kit - 100 assays
GWB-AXR060 100 assays Ask for price
Caspase-9 Colorimetric Assay Kit - 200 assays
GWB-AXR061 200 assays Ask for price
Caspase-5 Colorimetric Assay Kit - 100 assays
GWB-AXR070 100 assays Ask for price
Caspase-5 Colorimetric Assay Kit - 200 assays
GWB-AXR071 200 assays Ask for price
Caspase-4 Colorimetric Assay Kit - 100 assays
GWB-AXR086 100 assays Ask for price
Caspase-4 Colorimetric Assay Kit - 200 assays
GWB-AXR087 200 assays Ask for price
Caspase-10 Colorimetric Assay Kit - 100 assays
GWB-AXR078 100 assays Ask for price
Caspase-10 Colorimetric Assay Kit - 200 assays
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Caspase-3 Colorimetric Assay Kit - 25 assays
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Caspase-1 Colorimetric Assay Kit - 25 assays
GWB-AXR030 25 assays Ask for price
Caspase-8 Colorimetric Assay Kit - 25 assays
GWB-AXR038 25 assays Ask for price
Caspase-6 Colorimetric Assay Kit - 25 assays
GWB-AXR046 25 assays Ask for price
Caspase-2 Colorimetric Assay Kit - 25 assays
GWB-AXR054 25 assays Ask for price
Caspase-9 Colorimetric Assay Kit - 25 assays
GWB-AXR062 25 assays Ask for price
Caspase-5 Colorimetric Assay Kit - 25 assays
GWB-AXR072 25 assays Ask for price
Caspase-4 Colorimetric Assay Kit - 25 assays
GWB-AXR089 25 assays Ask for price
Caspase-10 Colorimetric Assay Kit - 25 assays
GWB-AXR079 25 assays Ask for price
LDH Based Cell Cytotoxicity Assay, Catalog: CPT-0101
CPT-0101 500 reactions
EUR 380
EnzyLight Cytotoxicity Assay Kit
ECTX-100 100
EUR 309
GWB-AXR029-200T - Caspase-1 Colorimetric Assay Kit - 200 assays
GWB-AXR029-200T 200assays
EUR 839
Basic Cytotoxicity Test Assay Kit
969 125
EUR 173
Total Cytotoxicity Test Assay Kit
972 250
EUR 670
Bioluminescence Cytotoxicity Assay Kit
55R-1367 500 assays
EUR 240
Description: Assay Kit for detection of Bioluminescence Cytotoxicity in the research laboratory
Bioluminescence Cytotoxicity Assay Kit
GWB-AXR195 500 assays Ask for price
Bioluminescence Cytotoxicity Assay Kit
K312-500 each
EUR 294
Caspase-3 DEVD-R110 Fluorometric and Colorimetric Assay Kit (100 assays)
30008-2 1KIT
EUR 459.6
Description: Minimum order quantity: 1 unit of 1KIT
Caspase-8 IETD-R110 Fluorometric and Colorimetric Assay Kit (100 assays)
30011-2 1KIT
EUR 459.6
Description: Minimum order quantity: 1 unit of 1KIT
Caspase-8 IETD-R110 Fluorometric and Colorimetric Assay Kit (25 assays)
30011-1 1KIT
EUR 244.8
Description: Minimum order quantity: 1 unit of 1KIT
Neutral Red Cell Cytotoxicity Assay Kit
K447-1000 each
EUR 379.2
AK Bioluminescence Cytotoxicity Assay Kit
K2026-500 500 assays
EUR 202
Description: Detects cytotoxicity based on adenylate kinase (AK), high throughput screening (HTS).
Crystal Violet Cell Cytotoxicity Assay Kit
K329-1000 each
EUR 379.2
Acid Phosphatase Cell Cytotoxicity Assay Kit
K937-500 each
EUR 444
WST-NR-CV Combined Cytotoxicity Assay Kit
K543-1000 each
EUR 810
Amplite® Colorimetric D-Lactate Dehydrogenase (LDH) Assay Kit
13809-200Tests 200 Tests
EUR 334
Description: Lactate dehydrogenase (LDH) is an oxidoreductase enzyme that catalyzes the interconversion of pyruvate and lactate.
Amplite® Colorimetric L-Lactate Dehydrogenase (LDH) Assay Kit
13813-200Tests 200 Tests
EUR 334
Description: Lactate dehydrogenase (LDH) is an oxidoreductase enzyme that catalyzes the interconversion of pyruvate and lactate.
MTT Cell Proliferation and Cytotoxicity Assay Kit
E-CK-A341-1000Assays 1000 Assays
EUR 228
MTT Cell Proliferation and Cytotoxicity Assay Kit
E-CK-A341-500Assays 500 Assays
EUR 136
Cell Proliferation and Cytotoxicity MTT Assay Kit
C0210-100 100 Assays
EUR 198
Cell Proliferation and Cytotoxicity MTT Assay Kit
C0210-500 500 Assays
EUR 360
Cell Proliferation and Cytotoxicity MTT Assay Kit
C0210-501 5000 Assays
EUR 1485.6
MTT Cell Proliferation and Cytotoxicity Assay Kit
AR1156 1 kit (for 500 assays)
EUR 115.2
MTT Cell Proliferation and Cytotoxicity Assay Kit
abx090676-500tests 500 tests
EUR 284.4
MTT Cell Proliferation and Cytotoxicity Assay Kit
abx090676-100l 100 µl
EUR 212.5
MTT Cell Proliferation and Cytotoxicity Assay Kit
abx090676-1ml 1 ml Ask for price
MTT Cell Proliferation and Cytotoxicity Assay Kit
abx090676-200l 200 µl Ask for price
MTT Cell Proliferation and Cytotoxicity Assay Kit
E-CK-A341-each each Ask for price
Description: Viability/Proliferation/Cytotoxicity
AMP Colorimetric Assay Kit
K229-100 each
EUR 692.4
ATP Colorimetric Assay Kit
E-BC-K157-M-48T 48T
EUR 2
Description: Quantitative
ATP Colorimetric Assay Kit
E-BC-K157-M-96T 96T
EUR 280
Description: Quantitative
ATP Colorimetric Assay Kit
E-BC-K157-M-each each Ask for price
Description: Quantitative
ATP Colorimetric Assay Kit
E-BC-K157-S-100Assays 100 Assays
EUR 280
Description: Quantitative
ATP Colorimetric Assay Kit
E-BC-K157-S-50Assays 50 Assays
EUR 2
Description: Quantitative
ATP Colorimetric Assay Kit
E-BC-K157-S-each each Ask for price
Description: Quantitative
H2S Colorimetric Assay Kit
E-BC-K355-M-48T 48T
EUR 15
Description: Quantitative
H2S Colorimetric Assay Kit
E-BC-K355-M-96T 96T
EUR 220
Description: Quantitative
H2S Colorimetric Assay Kit
E-BC-K355-M-each each Ask for price
Description: Quantitative
Heme Colorimetric Assay Kit
K672-100 each
EUR 588
Iron Colorimetric Assay Kit
K2069-100 100 assays
EUR 547
Description: Detects iron concentration, highly sensitive.
Zinc Colorimetric Assay Kit
K387-100 each
EUR 588
Iron Colorimetric Assay Kit
K390-100 each
EUR 660
Urea Colorimetric Assay Kit
K375-100 each
EUR 646.8
HDAC colorimetric assay kit
TBS2065 100 tests
EUR 289
Iron Colorimetric Assay Kit
E-BC-K139-M-48T 48T
EUR 150
Description: Quantitative
Iron Colorimetric Assay Kit
E-BC-K139-M-500Assays 500 Assays
EUR 550
Description: Quantitative
Iron Colorimetric Assay Kit
E-BC-K139-M-96T 96T
EUR 22
Description: Quantitative
Iron Colorimetric Assay Kit
E-BC-K139-S-100Assays 100 Assays
EUR 220
Description: Quantitative
Iron Colorimetric Assay Kit
E-BC-K139-S-50Assays 50 Assays
EUR 15
Description: Quantitative
Iron Colorimetric Assay Kit
E-BC-K139-S-each each Ask for price
Description: Quantitative
CytoX-Red Cell Proliferation/Cytotoxicity Assay Kit
OP-0004 10x96 assays
EUR 474.12
Cell Meterâ„¢ Fluorimetric Cell Cytotoxicity Assay Kit
22781-1000Tests 1000 Tests
EUR 222
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.
Cell Meterâ„¢ Fluorimetric Cell Cytotoxicity Assay Kit
22782-5000Tests 5000 Tests
EUR 897
Description: Our Cell Meter™ assay kits are a set of tools for monitoring cell viability.
PTP1B Colorimetric Assay Kit
30019 96 rxns.
EUR 425
Description: Protein phosphorylation is one of the most important post-translational_x000D_modification processes. Phosphorylation is reversibly regulated by Protein Kinases (PKs) and_x000D_Protein Phosphatases (PTPs). PTP1B (PTPN1) is known to catalyze dephosphorylation of_x000D_insulin receptor kinases and plays a critical role in insulin signaling. The PTP1B Colorimetric_x000D_Assay Kit is designed to measure PTP1B activity for screening and profiling applications, in a_x000D_homogeneous assay with no time-consuming washing steps. The PTP1B Colorimetric Assay Kit is optimized for both_x000D_continuous and end-point assay formats.
Hemin Colorimetric Assay Kit
K2215-100 100 assays
EUR 542
Description: Detects hemin, highly sensitive.
Cobalt Colorimetric Assay Kit
K505-100 each
EUR 548.4
Nickel Colorimetric Assay Kit
K510-100 each
EUR 548.4
Malate Colorimetric Assay Kit
K2139-100 100 assays
EUR 542
Description: Detects malate, accurate.
Malate Colorimetric Assay Kit
K637-100 each
EUR 588
WST-1 Cell Proliferation and Cytotoxicity Assay Kit
AR1158 1 kit (for 100 assays)
EUR 103.2
WST-1 Cell Proliferation and Cytotoxicity Assay Kit
AR1159 1 kit (for 500 assays)
EUR 157.2
WST-1 Cell Proliferation and Cytotoxicity Assay Kit
APB0003-25 5ml
EUR 0.1
Calcium Colorimetric Assay Kit
GWB-AXR220 250 assays Ask for price
Acetate Colorimetric Assay Kit
K658-100 each
EUR 614.4
Formate Colorimetric Assay Kit
K653-100 each
EUR 698.4
Calcium Colorimetric Assay Kit
K2067-250 250 assays
EUR 427
Description: Detects calcium concentration, sensitive.
Acetate Colorimetric Assay Kit
K2209-100 100 assays
EUR 437
Description: Detects acetate, sensitive.
Calcium Colorimetric Assay Kit
K380-250 each
EUR 516
Ammonia Colorimetric Assay Kit
K370-100 each
EUR 646.8
Ethanol Colorimetric Assay kit
TBS2090 100 tests
EUR 259
Nitrite Colorimetric Assay Kit
E-BC-K070-S-100Assays 100 Assays
EUR 150
Description: Quantitative
Nitrite Colorimetric Assay Kit
E-BC-K070-S-50Assays 50 Assays
EUR 12
Description: Quantitative
Nitrite Colorimetric Assay Kit
E-BC-K070-S-each each Ask for price
Description: Quantitative
Formate Colorimetric Assay Kit
E-BC-K1100-M-96T 96T
EUR 400
Description: Quantitative
Formate Colorimetric Assay Kit
E-BC-K1100-M-each each Ask for price
Description: Quantitative
Sucrose Colorimetric Assay Kit
E-BC-K161-S-100Assays 100 Assays
EUR 260
Description: Quantitative
Sucrose Colorimetric Assay Kit
E-BC-K161-S-50Assays 50 Assays
EUR 18
Description: Quantitative
Sucrose Colorimetric Assay Kit
E-BC-K161-S-each each Ask for price
Description: Quantitative
Ethanol Colorimetric Assay Kit
E-BC-K891-M-48T 48T
EUR 260
Description: Quantitative
Ethanol Colorimetric Assay Kit
E-BC-K891-M-500Assays 500 Assays
EUR 1100
Description: Quantitative
Ethanol Colorimetric Assay Kit
E-BC-K891-M-96T 96T
EUR 38
Description: Quantitative
CytoX-Violet Cell Proliferation/Cytotoxicity Assay Kit 
OP-0005
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 20x96 assays
  • 5x96 assays
  • 10x96 assays
  • 20x96 assays
Chloride Colorimetric Assay Kit
K530-100 each
EUR 430.8
Tyrosine Colorimetric Assay Kit
K573-100 each
EUR 660
Fumarate Colorimetric Assay Kit
K633-100 each
EUR 614.4
Chitosan Colorimetric Assay Kit
K995-100 each
EUR 679.2
Fructose Colorimetric Assay Kit
E-BC-K134-S-50Assays 50 Assays
EUR 200
Description: Quantitative
Fructose Colorimetric Assay Kit
E-BC-K134-S-each each Ask for price
Description: Quantitative
Glycerol Colorimetric Assay Kit
E-BC-K340-M-48T 48T
EUR 185
Description: Quantitative
Glycerol Colorimetric Assay Kit
E-BC-K340-M-96T 96T
EUR 280
Description: Quantitative
Glycerol Colorimetric Assay Kit
E-BC-K340-M-each each Ask for price
Description: Quantitative
ADP Colorimetric Assay Kit II
K356-100 each
EUR 686.4
Colorimetric DTT Assay kit
DTT100C 100 assays
EUR 221.78
Description: This product includes 1 ml of 10x Assay buffer, 0.2 ml of 10 x Reagent A, 0.2 ml of 10 x Reagent B and 0.5 ml of 10x Reagent C.
Phosphate Colorimetric Assay Kit
GWB-AXR228 500 assays Ask for price
Phosphate Colorimetric Assay Kit
K410-500 each
EUR 379.2
Glutamine Colorimetric Assay Kit
K556-100 each
EUR 705.6
Magnesium Colorimetric Assay Kit
K2068-100 100 assays
EUR 436
Description: Detects magnesium concentration, sensitive.
Phosphate Colorimetric Assay Kit
k2074-500 500 assays
EUR 245
Description: Detects phosphate, sensitive.
Glutamine Colorimetric Assay Kit
K2084-100 100 assays
EUR 504
Description: Detects glutamine, sensitive.
Glutamate Colorimetric Assay Kit
K2133-100 100 assays
EUR 557
Description: Detects glutamate, simple.
Magnesium Colorimetric Assay Kit
K385-100 each
EUR 574.8
Glutamate Colorimetric Assay Kit
K629-100 each
EUR 646.8
Urea Colorimetric Assay Kit II
K376-100 each
EUR 646.8
Zinc -Zn- Colorimetric Assay Kit
E-BC-K137-M-48T 48T
EUR 150
Description: Quantitative
Zinc -Zn- Colorimetric Assay Kit
E-BC-K137-M-500Assays 500 Assays
EUR 500
Description: Quantitative
Zinc -Zn- Colorimetric Assay Kit
E-BC-K137-M-96T 96T
EUR 22
Description: Quantitative
Cytochrome Oxidase Activity Colorimetric Assay Kit
K287-100 each
EUR 646.8
Cytochrome Oxidase Activity Colorimetric Assay Kit
K2020-100 100 assays
EUR 485
Description: Detects cytochrome oxidase activity, high throughput screening (HTS).
Zinc Assay Kit (Colorimetric)
MET-5138 100 assays
EUR 410
Isocitrate Colorimetric Assay Kit
K656-100 each
EUR 568.8
Hexokinase Colorimetric Assay Kit
K2179-100 100 assays
EUR 538
Hemoglobin Colorimetric Assay Kit
K219-200 each
EUR 457.2
Hexokinase Colorimetric Assay Kit
K789-100 each
EUR 718.8
Glutathione Colorimetric Assay Kit
55R-1351 100 assays
EUR 567
Description: Assay Kit for detection of Glutathione activity in the research laboratory

The HIV-positive price was 1.2% in the management group, and incentives prompted a 4.7 share level (95% CI 0.5 to 8.9) increased proportion of HIV-positive detection. Incentives additionally induced earlier testing, suggesting diminished procrastination. This means that info with appropriately timed small monetary incentives can enhance HIV testing and detection of recent instances in the overall inhabitants in LMIC settings. Both assessments explored supplier views and clinic dynamics associated to the introduction of LA ART and had been analyzed utilizing thematic content material evaluation. The Consolidated Framework for Implementation Research (CFIR) was drawn on because the conceptual framework underpinning improvement of a mannequin depicting study findings.